发明名称 |
B-cell epitopes derived from Pseudomonas aeruginosa outer membrane protein PA4710, antibodies and use in diagnosis and therapy |
摘要 |
An object is to provide: a protein antigen or a peptide antigen usable as a vaccine composition which has an ability to practically prevent or treat a Pseudomonas aeruginosa infection, and which can cope with the diversity of clinical isolates derived from patients with a Pseudomonas aeruginosa infection; and an antibody directed against the antigen. The present invention provides a protein antigen or a peptide antigen and an antibody directed against these, which are for use in diagnosis, prevention, or treatment of a disease associated with Pseudomonas aeruginosa. According to the present invention, a protein or a peptide derived from a Pseudomonas aeruginosa-outer membrane protein PA4710, and an antibody directed against these are provided, which are for use in diagnosis, prevention, or treatment of a disease associated with Pseudomonas aeruginosa.
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申请公布号 |
EP2175017(A1) |
申请公布日期 |
2010.04.14 |
申请号 |
EP20080777718 |
申请日期 |
2008.06.30 |
申请人 |
MEIJI SEIKA KAISHA LTD. |
发明人 |
TANAKA, JIRO;NAGASO, HIROSHI;KUMAGAI, MASASHI;OTSUKA, KEIKO;AKABANE, HIROTOMO;SUZUKI, TAKAHISA |
分类号 |
C12N15/09;A61K39/104;A61K39/395;A61P31/04;C07K14/21;C07K16/12;C12N5/10;C12P21/08;G01N33/569 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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