发明名称 |
Anti-tumor activity of small double-stranded oligodeoxynucleotides targeting telomerase RNA |
摘要 |
<p>The invention refers to an antitumor and/or anti-metastatic therapeutic, comprising siDNA oligonucleotides that bind to one or more RNA target regions of the RNA component of telomerase. The siDNA oligonucleotides comprise of one strand which is fully complementary to the template region of the RNA component of Telomerase and a second strand partially complementary to the antisense strand. The siDNA oligos bind the Telomerase RNA and lead to its inactivation.</p> |
申请公布号 |
EP2175023(A1) |
申请公布日期 |
2010.04.14 |
申请号 |
EP20090075334 |
申请日期 |
2009.07.24 |
申请人 |
THE UNIVERSITY OF ZURICH |
发明人 |
MOELLING, KARIN PROF. DR. |
分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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