发明名称 |
NON-HUMAN MAMMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES |
摘要 |
The invention provides knock-in non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing knock-in cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention. |
申请公布号 |
WO2010039900(A2) |
申请公布日期 |
2010.04.08 |
申请号 |
WO2009US59131 |
申请日期 |
2009.09.30 |
申请人 |
ALIVA BIOPHARMACEUTICALS, INC.;GREEN, LARRY;SHIZUYA, HIROAKI |
发明人 |
GREEN, LARRY;SHIZUYA, HIROAKI |
分类号 |
C12N15/13;A01K67/027;A61K39/395;C07K16/18 |
主分类号 |
C12N15/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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