发明名称 |
SUPERCRITICAL FLUID LOADING OF POROUS MEDICAL DEVICES WITH BIOACTIVE AGENTS |
摘要 |
Described herein are implantable medical devices that can be coated with polymers and/or bioactive agents with the aid of supercritical fluids and methods for coating the devices. The medical devices described herein can have at least a portion of their surface made of or formed from a porous material. The supercritical fluids are used as a carrier for the bioactive agents described. Once the bioactive agents are carried to the medical device surface, they are sequestered there, preferably in the pores. The supercritical fluid is sprayed onto the medical devices achieving precipitation of the fluid. If appropriate conditions are used in the area of precipitation, bioactive agents can penetrate into the pores of the medical device before coming out of solution and expanding. |
申请公布号 |
WO2010039644(A2) |
申请公布日期 |
2010.04.08 |
申请号 |
WO2009US58585 |
申请日期 |
2009.09.28 |
申请人 |
MEDTRONIC VASCULAR INC.;BERGLUND, JOSEPH |
发明人 |
BERGLUND, JOSEPH |
分类号 |
A61L27/34;A61L27/54;A61L29/08;A61L29/16;A61L31/10;A61L31/16;B05D1/02 |
主分类号 |
A61L27/34 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|