An injection apparatus (1) comprising a safeguard mechanism for assuring complete mixing of a multi-chamber ampoule (11a) prior to injection, further comprising a metering and/or actuating element and a housing, the metering and/or actuating element only being released by the safeguard mechanism after mixing of the multi-chamber ampoule, characterized in that the safeguard mechanism blocks the metering and/or actuating element prior to mixing by way of a purely axial mechanism of action.