A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating polycystic kidney disease in a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. Methods of treating in polycystic kidney disease in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.
申请公布号
CA2738768(A1)
申请公布日期
2010.04.08
申请号
CA20092738768
申请日期
2009.10.02
申请人
GENZYME CORPORATION
发明人
SIEGEL, CRAIG;BASTOS, CECILIA M.;HARRIS, DAVID J.;DIOS, ANGELES;LEE, EDWARD;SILVA, RICHARD;CUFF, LISA M.;LEVINE, MIKAELA;CELATKA, CASSANDRA A.;JOZAFIAK, THOMAS H.;VINICK, FREDERIC;XIANG, YIBIN;KANE, JOHN;LIAO, JUNKAI