发明名称 |
NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE |
摘要 |
<p>A compound represented by general formula (I), a pharmaceutically acceptable salt thereof, or a solvate of the compound or salt has an Aß production inhibitory activity or BACE 1 inhibitory activity, and is thus useful as an agent for treating neurodegenerative diseases caused by Aß as typified by Alzheimer's disease. (In the formula, ring A represents a C6-14 aryl group or the like; L represents -NRLCO- (wherein RL represents a hydrogen atom or the like) or the like; ring B represents a C6-14 aryl group or the like; X represents a C1-3 alkylene group or the like; Y represents a C1-3 alkylene group or the like; Z represents an oxygen atom or the like; R1 and R2 each independently represents a hydrogen atom or the like; and R3, R4, R5 and R6 each independently represents a hydrogen atom, a halogen atom or the like.)</p> |
申请公布号 |
WO2010038686(A1) |
申请公布日期 |
2010.04.08 |
申请号 |
WO2009JP66728 |
申请日期 |
2009.09.28 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD.;MOTOKI TAKAFUMI;TAKEDA KUNITOSHI;KITA YOICHI;TAKAISHI MAMORU;SUZUKI YUICHI;ISHIDA TASUKU |
发明人 |
MOTOKI TAKAFUMI;TAKEDA KUNITOSHI;KITA YOICHI;TAKAISHI MAMORU;SUZUKI YUICHI;ISHIDA TASUKU |
分类号 |
C07D513/04;A61K31/542;A61P25/00;A61P25/28;A61P43/00 |
主分类号 |
C07D513/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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