METHOD OF TREATING HORMONAL DEFICIENCY IN WOMEN UNDERGOING ESTROGEN REPLACEMENT THERAPY

摘要

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition that alleviates endometrial hyperplasia, a side effect of estrogen replacement therapy for women. SOLUTION: The pharmaceutical composition contains an estrogen compound of therapeutically effective amount, a non-aromatizing androgenic compound of a therapeutically effective amount and a pharmaceutically acceptable carrier. The estrogen compound is selected from estrone, 17α-estradiol, 17β-estradiol, equilin, 17α-dihydroequilin, 17β-dihydroequilin, equilenin, 17α-dihydroequilenin, 17β-dihydroequilenin,Δ8,9-dehydroestrone, 17α-Δ8,9-dehydroestradiol, 17β-Δ8,9-dehydroestradiol, ethynylestradiol and the like. The non-aromatizing androgenic compound is selected from oxandrolone, oxymetholone, stanozolol, danazol and the like. COPYRIGHT: (C)2010,JPO&INPIT