发明名称 |
SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF |
摘要 |
<p>The application relates to an immoalditol compound for selectively inhibiting glycosidases, a prodrug thereof and a pharmaceutical composition comprising the compound or the prodrug The application also relates to the use of the immoalditol compound for treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-G1cNAc Such diseases and disorders include neurodegenerative diseases, tauopathy, cancers, and cardiac disorders</p> |
申请公布号 |
WO2010037207(A1) |
申请公布日期 |
2010.04.08 |
申请号 |
WO2009CA01302 |
申请日期 |
2009.09.16 |
申请人 |
SIMON FRASER UNIVERSITY;VOCADLO, DAVID, JARO;MCEACHERN, ERNEST, JOHN |
发明人 |
VOCADLO, DAVID, JARO;MCEACHERN, ERNEST, JOHN |
分类号 |
C07D207/12;A61K31/40;C12Q1/40 |
主分类号 |
C07D207/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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