发明名称 SECRETORY CELL-CONTAINING MACROBEADS COMPRISING SEAKEM GOLD AGAROSE, AND USES THEREOF
摘要 The invention describes the manufacture and use of secretory cell containing bead structures that are coated with agarose. The beads, which are preferably 4 mm-12 mm in diameter, and which preferably contain islets, are made of a particular agarose, i.eagarose which has a sulfate content of less than 0.2 wt % but greater than zero, a pyruvate content of 0-0.1 wt %, and a Kjeldahl nitrogen content of 0-0.04 wt %. The gels found from the agarose exhibit a gel strength of at least 1200 g/cm2 (1.0 wt % concentration), substantial absence of DNA binding in 0.07 M or less tris acetate buffer, and an EEO at 1.0 wt % agarose concentration of 0.05 or less.
申请公布号 EP1928249(A4) 申请公布日期 2010.04.07
申请号 EP20060803714 申请日期 2006.09.14
申请人 THE ROGOSIN INSTITUTE, INC. 发明人 GAZDA, LAWRENCE;SMITH, BARRY
分类号 A01N65/00;C12N5/071 主分类号 A01N65/00
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