SELF COUPLING RECOMBINANT ANTIBODY FUSION PROTEINS

摘要

A compound comprising three components A, B, and C, which components are covalently bound forming the compound having the structure A-B-C wherein
component A has a specific binding affinity for antigens,
component B is covalently linked to component A
component C is a compound having an alkylated purin or pyrimidin moiety such as guanin, cytosin or a Coenzyme A moiety and linked thereto a moiety having a physiological effect with the proviso that
component B has an catalytical or acceptor activity to couple component C with covalently coupled components A-B.