发明名称 |
DEGRADABLE HYDROPHILIC BLOCK COPOLYMERS WITH IMPROVED BIOCOMPATIBILITY FOR SOFT TISSUE REGENERATION |
摘要 |
<p>The present application discloses biodegradable polymers, to porous and other materials comprising such polymers, and to various medical uses of such materials, including use as a scaffold for supporting cell adhesion or the in-growth for regeneration of tissue. The polymer is of the formula A-O—(CHR1CHR2O)n—B wherein A is a poly(lactide-co-glycolide) residue, the molar ratio of (i) lactide units [—CH(CH3)—COO—] and (ii) glycolide units [—CH2—COO—] in the poly(lactide-co-glycolide) residue being in the range of 80:20 to 10:90, B is either a poly(lactide-co-glycolide) residue or hydrogen, C1-6-alkyl or hydroxy protecting groups, one of R1 and R2 is hydrogen or methyl, and the other is hydrogen, n is 10-1000, the molar ratio of (iii) polyalkylene glycol units [—(CHR1CHR2O)—] to the combined amount of (i) lactide units and (ii) glycolide units in the poly(lactide-co-glycolide) residue(s) is at the most 14:86, and the molecular weight of the copolymer is at least 20,000 g/mol.</p> |
申请公布号 |
EP1996643(B8) |
申请公布日期 |
2010.04.07 |
申请号 |
EP20070711258 |
申请日期 |
2007.03.07 |
申请人 |
COLOPLAST A/S |
发明人 |
VANGE, JAKOB;SCHWACH-ABDELLAOUI, KHADIJA;EVERLAND, HANNE;NIELSEN, PETER, SYLVEST;NIELSEN, BRIAN;JESPERSEN, LENE, KARIN;NIELSEN, LENE, FELDSKOV |
分类号 |
C08G63/664;A61L15/26;A61L27/18;A61L27/56;C08G81/00;C08J9/00;C08J9/28 |
主分类号 |
C08G63/664 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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