发明名称 |
PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS |
摘要 |
<p>Novel iminium-type coupling agents containing proton acceptors in their iminium moiety, which can be used beneficially as coupling agents in various chemical polypeptide and/or polynucleotide syntheses, and are particularly useful as yield enhancing and racemization suppressing coupling agents for use in peptide syntheses, are disclosed. Further disclosed are a process of preparing such iminium-type coupling agents and their use in the preparation of polypeptides and/or polynucleotides.</p> |
申请公布号 |
EP2170822(A2) |
申请公布日期 |
2010.04.07 |
申请号 |
EP20080751362 |
申请日期 |
2008.05.15 |
申请人 |
LUXEMBOURG BIO TECHNOLOGIES LTD. |
发明人 |
ALBERICIO, FERNANDO;EL-FAHAM, AYMAN;LUXEMBOURG, YOAV;EWENSON, ARIEL |
分类号 |
C07D207/46;C07D213/89;C07D249/18;C07D295/13;C07D417/06;C07D471/04 |
主分类号 |
C07D207/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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