METHOD FOR PREPARING FMOC-BASED HYDROLYSABLE LINKERS
摘要
A novel process for the production of Fmoc (9H-fluoren-9-ylmethoxycarbonyl)-based compounds is provided, wherein a protecting group for the 9-hydroxymethyl group of the fluorene ring system is utilized. These compounds are useful for the modification of protein and peptide drugs.
申请公布号
EP2170821(A1)
申请公布日期
2010.04.07
申请号
EP20080759339
申请日期
2008.06.25
申请人
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A.
发明人
TURECEK, PETER;SIEKMANN, JUERGEN;NOE, CHRISTIAN;STOIBER, GERHARD
