| 发明名称 |
MONOCLONAL ANTIBODIES WHICH PROMOTE CENTRAL NERVOUS SYSTEM REMYELINATION |
| 摘要 |
Monoclonal IgM antibodies which promote central nervous system remyelination when given to a mammal afflicted with a demyelnating disease are disclosed. These antibodies show multi-organ autoreactivity, and recognize both surface and cytoplasmic determinants on glial cells.
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| 申请公布号 |
CA2188919(C) |
申请公布日期 |
2010.04.06 |
| 申请号 |
CA19952188919 |
申请日期 |
1995.04.27 |
| 申请人 |
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH |
发明人 |
RODRIGUEZ, MOSES;MILLER, DAVID J. |
| 分类号 |
C12N5/071;C12N15/02;A61K35/30;A61K38/00;A61K39/395;A61P25/00;A61P37/00;C07K16/18;C12N5/00;C12N5/10;C12N5/20;C12N15/13;C12P21/08;C12R1/91 |
主分类号 |
C12N5/071 |
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