The present invention provides a polynucleotide vector system used during polypeptide display that can be used to facilitate transfer of pools of polynucleotides encoding antigen binding proteins of interest. The present invention also provides methods that allow seamless conversion of pools of polynucleotides encoding antigen binding proteins using a restriction enzyme digestion and ligation strategy.
申请公布号
WO2010036856(A2)
申请公布日期
2010.04.01
申请号
WO2009US58316
申请日期
2009.09.25
申请人
WYETH LLC;HUFTON, SIMON EVAN;FINLAY, WILLIAM, JAMES