发明名称 |
IMPROVED PROTEIN PRODUCTION IN A HOST |
摘要 |
Recombinant DNA constructs that provide for expression of desired target proteins as protein bodies in various host cells, tissues, and organisms are disclosed. Such recombinant DNA constructs contain a heterologous polynucleotide comprising an ER luminal folding chaperone interacting domain (CID), a sequence that codes for a trans-membrane domain (TMD); and a sequence that codes for a protein-protein interaction domain (PPID) that are operably linked to a sequence encoding the desired target protein. Proteins obtained from the constructs, host cells containing the constructs, and methods for obtaining desired target proteins encoded by the constructs are also disclosed. |
申请公布号 |
WO2010011679(A3) |
申请公布日期 |
2010.04.01 |
申请号 |
WO2009US51295 |
申请日期 |
2009.07.21 |
申请人 |
DONALD DANFORTH PLANT SCIENCE CENTER;FAUQUET, CLAUDE, M.;ABHARY, MOHAMMAD |
发明人 |
FAUQUET, CLAUDE, M.;ABHARY, MOHAMMAD |
分类号 |
C12N15/63;C12N15/67;C12P21/00 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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