发明名称 |
INDIVIDUAL 5-FLUOROURACILE DOSE OPTIMIZATION IN FOLFIRI TREATMENT |
摘要 |
The present invention belongs to the field of improved personalized medicine. More precisely, the present invention relates to a method for progressively optimizing the 5 -FU dose administered by continuous infusion in patients treated by a FOLFIRI regimen or a similar regimen, based on the 5 -FU plasmatic concentration measured during the previous 5 -FU continuous infusion and on a herein described decision algorithm. The present invention also relates to a method for treating a cancer patient in which the 5 -FU dose administered in continuous infusion in each FOLFIRI or similar treatment cycle is optimized using the decision algorithm according to the invention. |
申请公布号 |
WO2010035076(A1) |
申请公布日期 |
2010.04.01 |
申请号 |
WO2008IB55626 |
申请日期 |
2008.09.26 |
申请人 |
CENTRE REGIONAL DE LUTTE CONTRE LE CANCER D'ANGERS;UNIVERSITE D'ANGERS;GAMELIN, ERICK;BOISDRON-CELLE, MICHELE;MOREL, ALAIN |
发明人 |
GAMELIN, ERICK;BOISDRON-CELLE, MICHELE;MOREL, ALAIN |
分类号 |
A61K31/4745;A61K31/513;A61K31/519;A61K39/395;A61P39/00 |
主分类号 |
A61K31/4745 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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