摘要 |
Provided is an efficient production method which is designed for an industrial production process and is superior in operability, purity, etc. As a result of conducting the study on an efficient production method which is designed for an industrial production process, and is superior in operability, and with which a high purity intermediate can be obtained, it found that a method with which the number of steps (of eliminating diamino acid) can be reduced, purification by chromatography is not needed, and an intermediate can be obtained at a high purity, and found a method for producing a cyclic peptide compound known to have an anti-HCV activity, a peptide intermediate useful for the production, and a method for producing the intermediate, which are relevant to the present invention. In the method, it is not necessary to repeat Edman degradation, it becomes possible to supply a large amount of the peptide intermediate and the cyclic peptide compound without performing the step of chromatography associated with the reaction.
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