发明名称 PEPTIDE COMPOUND AND METHOD FOR PRODUCING THE SAME
摘要 Provided is an efficient production method which is designed for an industrial production process and is superior in operability, purity, etc.  As a result of conducting the study on an efficient production method which is designed for an industrial production process, and is superior in operability, and with which a high purity intermediate can be obtained, it found that a method with which the number of steps (of eliminating diamino acid) can be reduced, purification by chromatography is not needed, and an intermediate can be obtained at a high purity, and found a method for producing a cyclic peptide compound known to have an anti-HCV activity, a peptide intermediate useful for the production, and a method for producing the intermediate, which are relevant to the present invention.  In the method, it is not necessary to repeat Edman degradation, it becomes possible to supply a large amount of the peptide intermediate and the cyclic peptide compound without performing the step of chromatography associated with the reaction.
申请公布号 CA2738280(A1) 申请公布日期 2010.04.01
申请号 CA20092738280 申请日期 2009.09.18
申请人 ASTELLAS PHARMA INC. 发明人 ORII, RYOKI;KITAYAMA, MASATO;YAMANAKA, TOSHIO;OKUDA, SHINYA;SHIBAZAKI, MITSUYOSHI
分类号 C07K7/06;A61K38/00;A61P31/14;C07K7/64 主分类号 C07K7/06
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