发明名称 |
Atopic dermatitis inducer |
摘要 |
An atopic dermatitis inducer binding to a human own IgE antibody and activating mast cells and basophiles, which includes a purified human secretion fraction, or an antigenic molecule or an antigenic determinant in the purified fraction, and obtained through the following steps of: filtering a human secretion, removing insoluble matters and collecting the filtrate; mixing the filtrate with a ConA-affinity carrier and collecting the supernatant; and separating a component having a histamine-releasing activity from the supernatant by column chromatography. This inducer is effective in diagnosing and treating human atopic dermatitis.
|
申请公布号 |
US2010080854(A1) |
申请公布日期 |
2010.04.01 |
申请号 |
US20090461368 |
申请日期 |
2009.08.10 |
申请人 |
HIDE MICHIHIRO;TANAKA TOSHIHIKO;TANAKA AKIO;ISHII KAORI;SUZUKI HIDENORI |
发明人 |
HIDE MICHIHIRO;TANAKA TOSHIHIKO;TANAKA AKIO;ISHII KAORI;SUZUKI HIDENORI |
分类号 |
A61K35/55;A61P17/00;A61P37/08;C07K14/47;C07K16/42 |
主分类号 |
A61K35/55 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|