| 发明名称 |
Oncogenic-RAS-signal dependent lethal compounds |
| 摘要 |
Compounds with cancer cell specific lethality are provided. In particular, RAS-selective lethal compounds and compositions are provided. Also provided are methods of screening for such compounds and methods of treating a condition in a mammal, by administering to the mammal a therapeutically effective amount of such compounds or compositions.
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| 申请公布号 |
US2010081654(A1) |
申请公布日期 |
2010.04.01 |
| 申请号 |
US20090583579 |
申请日期 |
2009.08.21 |
| 申请人 |
STOCKWELL BRENT R;YANG WAN SEOK;SRIRAMARATNAM ROHITHA |
发明人 |
STOCKWELL BRENT R.;YANG WAN SEOK;SRIRAMARATNAM ROHITHA |
| 分类号 |
A61K31/5365;A61K31/437;C07D471/04;C07D498/14 |
主分类号 |
A61K31/5365 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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