发明名称 THERAPEUTIC USES OF HUMANIZED ANTIBODIES AGAINST ALPHA-4 INTEGRIN
摘要 The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host disease, tumor metastasis, nephritis, atopic dermatitis, psoriasis, myocardial ischemia, and acute leukocyte mediated lung injury.
申请公布号 US2010081793(A1) 申请公布日期 2010.04.01
申请号 US20080175116 申请日期 2008.07.17
申请人 ELAN PHARMACEUTICALS, INC. 发明人 BENDIG MARY M.;LEGER OLIVIER J.;SALDANHA JOSE;JONES TARRAN S.;YEDNOCK TED A.
分类号 C07K16/18;G01N33/53;A61K38/00;A61K39/395;A61P7/00;A61P29/00;A61P37/00;C07H21/04;C07K;C07K16/28;C07K16/46;C12N5/00;C12N5/10;C12N15/09;C12N15/13;C12P21/08;C12R1/91 主分类号 C07K16/18
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