发明名称 IN VITRO METHOD AND KIT FOR PROGNOSIS OR PREDICTION OF THE RESPONSE OF RHEUMATOID ARTHRITIS PATIENTS TO TREATMENT WITH TNF-ALPHA FACTOR BLOCKING AGENTS
摘要 In vitro method and kit for prognosis or prediction of response to treatment with TNF-alfa factor blocking agents by patients with rheumatoid arthritis, comprising determination of a blood sample from said patients of the degree of expression of at least one of the eight genes selected from the group: HLA-DRB3, EAT2, GNLY, CAMP, SLC2A3, IL2RB, MXD4 and TLR5 or combinations thereof, and comparison of said degree of expression with respect to the values of expression obtained from patients responding to the treatment and not responding thereto.
申请公布号 CA2738207(A1) 申请公布日期 2010.04.01
申请号 CA20092738207 申请日期 2009.09.18
申请人 FUNDACIO INSTITUT DE RECERCA DE L'HOSPITAL UNIVERSITARI VALL D'HEBRON 发明人 JULIA CANO, ANTONIO;MARSAL BARRIL, SARA
分类号 C12Q1/68 主分类号 C12Q1/68
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