| 摘要 |
<p>During intensive studies leading to the submitted invention, the inventors here found out that the peptide uroaktivin with the amino acid sequence SEQ ID NO: 1 binds and increases the enzymatic activity of urokinase and tissue plasminogenic activator. Thus according to the first aspect, the submitted invention assures the amino acid sequence of the peptide uroaktivin - SEQ ID NO: 1. The submitted invention also assures the use of the peptide uroaktivin for a more successful treatment of diseases or states in which the application of thrombolytics is indicated - such states are particularly acute coronary thromboses (acute myocardial infarction), acute ischemic brain strokes, acute pulmonary thromboembolisms, deep venous thromboses and acute arterial thromboembolisms - and for assuring patency of arteriovenous canules and intravenous catheters.</p> |
