Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-HT2A serotonin receptor
摘要
The present invention relates to processes for preparing phenyl-pyrazoles of Formula (I) and salts and pharmaceutical compositions thereof, useful as modulators of 5-HT2A serotonin receptor activity. The present invention also relates to intermediates used in the processes, and their preparation. The present invention also relates to crystalline forms of 5-HT2A serotonin receptor modulators, compositions thereof and methods of using the same.
申请公布号
ZA200808813(B)
申请公布日期
2010.03.31
申请号
ZA20080008813
申请日期
2008.10.15
申请人
ARENA PHARMACEUTICALS, INC.
发明人
GHARBAOUI, TAWFIK;SENGUPTA, DIPANJAN;KRISHNAN, ASHWIN M.;SHAH, NAINESH;MACIAS, MARK;HART, RYAN M.;LALLY, EDWARD A.;DUFFIELD, JONATHAN J.