发明名称 |
MHC MULTIMERS, METHODS FOR THEIR GENERATION, LABELING AND USE |
摘要 |
<p>The present invention describes novel methods to generate MHC multimers and methods to improve existing and new MHC multimers. The invention also describes improved methods for the use of MHC multimers in analysis of T-cells in samples including diagnostic and prognostic methods. Furthermore the use of MHC multimers in therapy are described, e.g. anti-tumour and anti-virus therapy, including isolation of antigen specific T-cells capable of inactivation or elimination of undesirable targeT-cells or isolation of specific T-cells capable of regulation of other immune cells.</p> |
申请公布号 |
EP2167536(A1) |
申请公布日期 |
2010.03.31 |
申请号 |
EP20080758304 |
申请日期 |
2008.07.03 |
申请人 |
DAKO DENMARK A/S |
发明人 |
BRIX, LISELOTTE;PEDERSEN, HENRIK;JAKOBSEN, TINA;SCHOELLER, JOERGEN;LOHSE, JESPER;BRUNSTEDT, KATJA;JACOBSEN, KIVIN |
分类号 |
C07K14/705;A61K38/17;A61K39/00;A61K47/48;A61P31/00;G01N33/50 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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