CROSSLINKED POLYALLYLAMINE OR ACID ADDITION SALT THEREOF, AND USE THEREOF FOR MEDICAL PURPOSES

摘要

Disclosed are a cross-linked polyallylamine or an acid addition salt thereof having both high phosphate adsorption capability and low degree of swelling, and a medical use thereof. A cross-linked polyallylamine or an acid addition salt thereof was provided, which is obtained by copolymerization of allylammonium dihydrogen phosphate with an acid addition salt of N , N '-diallyl-1,3-diaminopropane in an amount of 5 to 25 mol% with respect to the amount of the allylammonium dihydrogen phosphate, the cross-linked polyallylamine or an acid addition salt thereof having a phosphate adsorption capacity of 2.7 to 5.0 mmol/g; and a degree of swelling of 2.0 to 5.0. This cross-linked polyallylamine or an acid addition salt thereof is useful as a therapeutic or prophylactic agent for hyperphosphatemia.