摘要 |
A catalyst composition for a cross-coupling reaction comprising a nickel metal source, a fluorine source, and a nitrogen-containing heterocyclic compound having a specific structure, or a phosphine compound. Using this catalyst composition, a cross-coupled compound R 5 -R 6 (wherein R 5 and R 6 are an aryl or heteroaryl group, or a linear, branched or cyclic alkyl group or a linear, branched or cyclic alkenyl group) is produced with a high selectivity by allowing an organometallic compound of the formula (2) R 5 -MY 1 or the formula (3) R 5 -M-R 5 (wherein R 5 is the same as defined above, M is a Mg or Zn atom, and Y 1 is a halogen atom) to react with a compound of the formula (4) R 6 -Y 2 (wherein R 6 is the same as defined above, and Y 2 is a halogen atom, a methanesulfonate group, a toluenesulfonate group or a trifluoromethanesulfonate group). |