Disclosed herein are pyrazole glucokinase activators of the formula (I) wherein R to R are as defined in the specification and claims, useful for the treatment of metabolic diseases and disorders, preferably diabetes mellitus.
申请公布号
ZA200900166(B)
申请公布日期
2010.03.31
申请号
ZA20090000166
申请日期
2009.01.08
申请人
F. HOFFMANN-LA ROCHE AG.
发明人
BERTHEL, STEVEN JOSEPH;KESTER, ROBERT FRANCIS;MURPHY, DOUGLAS ERIC;PRINS, THOMAS JAY;RUEBSAM FRANK;SARABU, RAMAKANTH;TRAN, CHINH VIET;VOURLOUMIS, DIONISIOS
