摘要 |
Compounds of the formula (I)
and pharmaceutically acceptable salts thereof, wherein X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , R 1 , and Q 1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions of the central nervous system. |
申请人 |
OSI PHARMACEUTICALS, INC. |
发明人 |
ARNOLD, LEE, D.;CESARIO, CARA;COATE, HEATHER;CREW, ANDREW, PHILIP;DONG, HANQING;FOREMAN, KENNETH;HONDA, AYAKO;LAUFER, RADOSLAW;LI, AN-HU;MULVIHILL, KRISTEN, MICHELLE;MULVIHILL, MARK, JOSEPH;NIGRO, ANTHONY;PANICKER, BIJOY;STEINIG, ARNO, G.;SUN, YINGCHUAN;WENG, QINGHUA;WERNER, DOUGLAS, S.;WYLE, MICHAEL, J.;ZHANG, TAO |