Macrocyclic inhibitors of hepatitis C virus

摘要

Disclosed are macrocylic compounds of formula (I) having inhibitory activity on the replication of the hepatitis C virus (HCV), and the N-oxides, salts, and stereochemically isomeric forms thereof, wherein the variables are as defined in the specification; pharmaceutical compositions containing these compounds of formula (I) and processes for preparing compounds (I). Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also provided.