| 发明名称 |
HOMOGENEOUS ANTIBODY POPULATIONS. |
| 摘要 |
<p>The present invention is generally directed to methods of producing an increase in the enrichment and/or recovery of preferred forms of monoclonal antibodies. More particularly, the invention relates to methods for eliminating disulfide heterogeneity in the hinge region of recombinant IgG2 antibody proteins.</p> |
| 申请公布号 |
MX2010002683(A) |
申请公布日期 |
2010.03.26 |
| 申请号 |
MX20100002683 |
申请日期 |
2008.09.11 |
| 申请人 |
AMGEN INC. |
发明人 |
THOMAS M. DILLON;MARTIN ALLEN;PAVEL BONDARENKO;WENYAN SHEN;JETTE WYPYCH;ALAIN BALLAND;MARGARET SPEED RICCI;AMY GUO;JEONGHOON SUN;CHRIS VEZINA |
| 分类号 |
C07K16/00;A61K39/395;C07K16/28 |
主分类号 |
C07K16/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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