PEPTIDE-PRESENTING SURFACES FOR LONG-TERM CULTURE OF PLURIPOTENT CELLS
摘要
The present invention relates to methods of growing and maintaining pluripotent cells on an insoluble substrate that presents a peptide that binds to glycosaminoglycans, such as heparin. Specifically, methods of growing and maintaining pluripotent cells on substrates having a chemically defined surface presenting at least one peptide having basic amino acid residues separated by one or two hydrophobic amino acid residues.
申请公布号
WO2010033925(A2)
申请公布日期
2010.03.25
申请号
WO2009US57705
申请日期
2009.09.21
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;KIESSLING, LAURA, LEE;KLIM, JOSEPH, ROBERT;LI, LINGYIN