发明名称 BICYCLIC DIHYDROIMIDAZOLONE CGRP RECEPTOR ANTAGONISTS
摘要 Compounds of formula (I): wherein variables B, G1, G2, G3, G4, Ea, Eb, Ec, A1, A2, A3, A4, R6 and RPG and Y are as described herein, which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
申请公布号 CA2737711(A1) 申请公布日期 2010.03.25
申请号 CA20092737711 申请日期 2009.09.10
申请人 MERCK SHARP & DOHME CORP. 发明人 STUMP, CRAIG A.
分类号 A01N43/50;A61K31/405;A61K31/415 主分类号 A01N43/50
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