Disclosed are mGluR4 positive allosteric modulator ligands of general formula (I) and radiolabeled derivates, their use as therapeutic agents for the treatment of central nervous system disorders modulated by mGluR4 and as ligands for the labeling and diagnostic imaging of mGluR4 in mammals.
申请公布号
CA2737699(A1)
申请公布日期
2010.03.25
申请号
CA20092737699
申请日期
2009.08.24
申请人
MERCK SHARP & DOHME CORP.
发明人
MCCAULEY, JOHN A.;HESS, JOHN W.;LIVERTON, NIGEL J.;MCINTYRE, CHARLES J.;ROMANO, JOSEPH J.;RUDD, MICHAEL T.
