CONTROLLING INTRACELLULAR CALCIUM LEVELS ASSOCIATED WITH AN ISCHEMIC EVENT WITH O-DESULFATED HEPARIN

摘要

Described herein are methods for controlling the intracellular calcium concentration in a subject prior to experiencing an ischemic event, while experiencing an ischemic event, or while suffering from ischemia. The methods comprise administering an effective amount of O-desulfated heparin (ODSH, like 2-0 desulfated or 3-0 desulfated heparin) to the subject. The methods described herein are also useful in treating the symptoms associated with ischemic events or ischemia.