The present invention relates to a multi-stage process for producing substituted, optically active alcohols, comprising an enzyme-catalyzed synthesis step, in particular a synthesis step which is catalyzed by an alcohol dehydrogenase. The inventive method is particularly suitable for producing phenylephrine, i.e. 3-[(1R)-1-hydroxy-2-methylamino-ethyl]-phenol.
申请公布号
WO2010031776(A2)
申请公布日期
2010.03.25
申请号
WO2009EP61974
申请日期
2009.09.15
申请人
BASF SE;BREUER, MICHAEL;PLETSCH, ANDREAS;HAUER, BERNHARD;SIEGEL, WOLFGANG
发明人
BREUER, MICHAEL;PLETSCH, ANDREAS;HAUER, BERNHARD;SIEGEL, WOLFGANG