发明名称 BACULOVIRUS-BASED VACCINES
摘要 The invention relates to a recombinant baculovirus and a vaccine composition containing the recombinant baculovirus. The recombinant baculovirus comprises: (a) a nucleotide sequence coding extrinsic envelope proteins of virus; (b) the first promoter operatively connected to the envelope coding sequence; (c) a nucleotide sequence coding an antigenic protein; and (d) the second promoter operatively connected to the antigenic protein. The recombinant baculovirus of the invention realizes improved vaccine efficacy due to excellent induction capacities of cell-mediated immunity as well as humoral immunity response to a specific antigen (for example, L1 of HPV).
申请公布号 WO2009088256(A8) 申请公布日期 2010.03.25
申请号 WO2009KR00136 申请日期 2009.01.09
申请人 KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP;KIM, YOUNG-BONG;LEE, HEE JUNG;PARK, NURI;OH, YU KYOUNG 发明人 KIM, YOUNG-BONG;LEE, HEE JUNG;PARK, NURI;OH, YU KYOUNG
分类号 C12N15/48 主分类号 C12N15/48
代理机构 代理人
主权项
地址
您可能感兴趣的专利