NGAL-BINDING SIDEROPHORES AND USE THEREOF TO TREAT IRON DEFICIENCY AND IRON OVERLOAD
摘要
<p>The invention provides compositions comprising a lipocalin, such as NGAL, and a mammalian siderophore that are useful as iron chelators and iron donors. The invention also provides mammalian siderophore compounds of Formula (I): The invention further provides, methods of treatment and methods of diagnosis.</p>
申请公布号
WO2010033847(A1)
申请公布日期
2010.03.25
申请号
WO2009US57543
申请日期
2009.09.18
申请人
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;BARASCH, JONATHAN;DENG, SHIXIAN;BAO, GUANHU;LANDRY, DONALD, W.
发明人
BARASCH, JONATHAN;DENG, SHIXIAN;BAO, GUANHU;LANDRY, DONALD, W.