发明名称 |
LINCOSAMIDE DERIVATIVE, AND ANTIBACTERIAL AGENT COMPRISING THE SAME AS ACTIVE INGREDIENT |
摘要 |
<p>An objective of the present invention is to provide compounds of formula (I) or their pharmacologically acceptable salts or solvates wherein A represents aryl while R 1 represents a five- or six-membered monocyclic heterocyclic group, or A represents a four- to six-membered monocyclic heterocyclic group while R 1 represents aryl or a five- or six-membered monocyclic heterocyclic group; R 2 represents a hydrogen atom or C 1-6 alkyl; R 3 represents C 1-6 alkyl or C 3-6 cycloalkyl-C 1-4 alkyl; R 4 , R 5 , and R 6 represent a hydrogen atom; R 7 represents C 1-6 alkyl; and m is 1 to 3. The compounds are novel lincosamide derivatives that have a potent activity against resistant Streptococcus pneumoniae. Further, the compounds are usable as antimicrobial agents and are useful for preventing or treating bacterial infectious diseases.</p> |
申请公布号 |
EP2166015(A1) |
申请公布日期 |
2010.03.24 |
申请号 |
EP20080777056 |
申请日期 |
2008.05.30 |
申请人 |
MEIJI SEIKA KAISHA LTD. |
发明人 |
UMEMURA, EIJIROU;KUMURA, KOU;MASAKI, SATOMI;UEDA, KAZUTAKA;WAKIYAMA, YOSHINARI;SATO, YASUO;YAMAMOTO, MIKIO;AJITO, KEIICHI;WATANABE, TAKASHI;KAJI, CHIZUKO |
分类号 |
C07H15/16;A61K31/7052;A61K31/7056;A61K31/706;A61P11/00;A61P31/04 |
主分类号 |
C07H15/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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