发明名称 |
2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them |
摘要 |
<p>The present invention relates to (R,S) 2-aryl-propionic acids and derivatives, their single enantiomer (S) and to pharmaceutical compositions containing them, which are used in the prevention and treatment of tissue damage due to the exacerbated recruitment of polymorphonucleated neutrophils (PMN leukocytes) at inflammation sites. The present invention provides compounds for use in the treatment of transient cerebral ischemia, bullous pcmphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and damages caused by ischemia and reperfusion.</p> |
申请公布号 |
EP2166006(A1) |
申请公布日期 |
2010.03.24 |
申请号 |
EP20080164605 |
申请日期 |
2008.09.18 |
申请人 |
DOMPE' S.P.A. |
发明人 |
ALLEGRETTI, MARCELLO;ARAMINI, ANDREA;BIANCHINI, GIANLUCA;CESTA, MARIA CANDIDA |
分类号 |
C07D277/42;C07D263/48;A61K31/421;A61K31/427;A61P29/00 |
主分类号 |
C07D277/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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