There is provided at least one isolated antimicrobial peptide, wherein the peptide is a linear analog of hBD3 or a fragment thereof. In particular, there is provided a linear analog of hBD3 wherein the peptide has a reduced cytotoxicity to at least one cell compared to the wild type hBD3.
申请公布号
EP2010561(A4)
申请公布日期
2010.03.24
申请号
EP20070748666
申请日期
2007.04.27
申请人
SINGAPORE HEALTH SERVICES PTE LTD;AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
发明人
BEUERMAN, ROGER;ZHOU, LEI;LIU, SHOUPING;LI, JING;SURESH, ANITA;VERMA, CHANDRA SHEKHAR;TAN, DONALD