发明名称 Nucleic acid derivatives
摘要 A compound which comprises a backbone having a plurality of chiral carbon atoms, the backbone bearing a plurality of ligands each being individually bound to a chiral carbon atom of the plurality of chiral carbon atoms, the ligands including one or more pair(s) of adjacent ligands each containing a moiety selected from the group consisting of a naturally occurring nucleobase and a nucleobase binding group, wherein moieties of the one or more pair(s) are directly linked to one another via a linker chain; building blocks for synthesizing the compound; and uses of the compound, particularly in antisense therapy.
申请公布号 US7683164(B2) 申请公布日期 2010.03.23
申请号 US20080071275 申请日期 2008.02.19
申请人 BIO-RAD LABORATORIES INC. 发明人 SEGEV DAVID
分类号 C07H21/02;C12N15/09;A01N43/04;A61K31/439;A61K31/506;A61K31/513;A61K31/52;A61K31/675;A61K48/00;A61P1/04;A61P1/18;A61P7/00;A61P9/00;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P17/12;A61P19/02;A61P27/02;A61P29/00;A61P31/10;A61P31/12;A61P31/16;A61P31/18;A61P31/22;A61P35/00;A61P37/04;C07D239/52;C07D498/18;C07H5/04;C07H19/04;C07H21/04;C12P13/00;C12Q1/68 主分类号 C07H21/02
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