发明名称 |
HALENIC COMPOSITIONS OF ORGANIC COMPOUNDS |
摘要 |
FIELD: medicine. ^ SUBSTANCE: invention concerns a solid oral dosage form composition containing therapeutically effective amount of aliskiren or its pharmaceutically acceptable salt in amount exceeding 46 wt %. The oral dosage form represents a tablet or a film-coated tablet. Aliskiren tablet is made by wet granulation with using mixed organic solvents or organic binding solutions. ^ EFFECT: elimination of aqueous granulation provides high stability of the dosage form of aliskiren and prolonged shelf-life. ^ 18 cl, 2 ex |
申请公布号 |
RU2384328(C2) |
申请公布日期 |
2010.03.20 |
申请号 |
RU20060136090 |
申请日期 |
2005.03.16 |
申请人 |
NOVARTIS AG |
发明人 |
RIGASSI-DITRIKH PETRA GIZELA;SHMID MARTIN |
分类号 |
A61J3/10;A61K9/20;A61K9/28;A61K9/30;A61K31/00;A61K31/137;A61K31/16;A61K31/4166;A61P9/00;A61P9/10 |
主分类号 |
A61J3/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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