BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS

摘要

The invention provides methods that employ derivatives of 2-cyano-6-hydoxy- or 2-cyano-6-amino-benzothiazole, for example, in a bioluminogenic reaction. Also provided are novel compounds that can be used in the methods. The invention further provides methods for detecting or determining the presence of molecules and/or enzymes, the modulator activity of such molecules, and/or the activity of such enzymes. The methods are adaptable to high-throughput format.