发明名称 |
Recombinant vaccine viruses expressing IL-15 and methods of using the same |
摘要 |
<p>The invention is directed to compositions capable of augmenting the immunogenicity of a vaccine. The composition, or adjuvant, is administered to a mammal in need thereof in sequential or concurrent combination with a vaccine antigen. In one preferred aspect, the adjuvant is provided in the form of a recombinant poxvirus vector, such as a vaccinia virus vector, which comprises a nucleic acid sequence encoding IL-15.</p> |
申请公布号 |
AU2003297155(B2) |
申请公布日期 |
2010.03.18 |
申请号 |
AU20030297155 |
申请日期 |
2003.12.15 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
THOMAS A. WALDMANN;JAY A. BERZOFSKY;LIYANGE P. PERERA;SANG-KON OH |
分类号 |
A61K39/00;A61K39/21;A61K39/39 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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