| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method, a composition and a kit for improving oral bioavailability of a pharmaceutical agent inadequate of absorption from the gastrointestinal tract such as paclitaxel. Ž<P>SOLUTION: A combination of 9,10-dihydro-5-methoxy-9-oxo-N-[4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]phenyl]-4-acridinecarboxamide or a salt thereof, and paclitaxel with analogs or derivatives thereof, is provided. Ž<P>COPYRIGHT: (C)2010,JPO&INPIT Ž
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