DOCETAXEL LYOPHILIZED PARENTARAL FORMULATION FOR SAFE DRUG DELIVERY SYSTEM AND PROCESS OF MAKING THEREOF

摘要

A novel formulations of Docetaxel and process of making thereof, without using Polysorbate or Chremophor to avoid their known toxicological problems. Comprising the particularly Modified natural cyclodextrins, along with nonionic tensoactive plus additives,and a diluents, combined with the lyophilized Docetaxel in order to obtain a reconstituted solution that upon dilution in normal saline solution or 5 % dextrose solution.