DETECTION AND QUANTIFICATION OF ANTIGENS

摘要

The present invention provides compositions, kits, systems, and methods for detecting antigens in a biological sample, preferably HIV antigens and in particular a HIV-1 p24 antigen. A preferred p24 immuosystem has a wide dynamic range together with a high sensitivity. A preferred assay of the present invention uses a solid support coupled to a high affinity first antibody directed against an antigen together with a labeled second antibody binding to the same antigen.