发明名称 |
COMPOUNDS THAT MODULATE NEGATIVE-SENSE, SINGLE-STRANDED RNA VIRUS REPLICATION AND USES THEREOF |
摘要 |
The present invention relates to compounds that modulate the replication of negative-sense, single-stranded RNA viruses, such as influenza virus, and the use of such compounds. The invention relates to methods for increasing the titer of negative- sense, single-stranded RNA viruses, such as influenza virus, in substrates for virus propagation (e.g., tissue culture). The invention also relates to the use of compounds that decrease virus replication as antiviral agents. The invention further relates to methods for identifying compounds that modulate the replication of negative-sense, single-stranded RNA viruses, in particular, influenza virus. |
申请公布号 |
WO2009136979(A3) |
申请公布日期 |
2010.03.18 |
申请号 |
WO2009US01474 |
申请日期 |
2009.03.06 |
申请人 |
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY;SHAW, MEGAN, L.;HOFFMANN, HANS-HEINRICH;GARCIA-SASTRE, ADOLFO;PALESE, PETER |
发明人 |
SHAW, MEGAN, L.;HOFFMANN, HANS-HEINRICH;GARCIA-SASTRE, ADOLFO;PALESE, PETER |
分类号 |
A61K31/00;A61K31/4245;A61P31/16 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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